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Our projects

Ongoing Projects

  • Substitute member of the national network of researchers for the COST Action CA18216 – Network for Research in Vascular Aging; Period 05.11.2019 – 04.11.2023; Management Committee Member (România): Adrian Covic;
  • COST Action CA18122: “European Cholangiocarcinoma Network”; Project duration: 18.03.2019 –17.03.2023. Management Committee Member (România): Vasile Liviu Drug;
  • COST Action CA17104 Project title: “New diagnosis and therapeutic tools against multidrug resistant tumors” Project type: COST European Cooperation in Science & Technology – Action CA17104. Development period: 01.10.2018- 01.10.2022. Management Committee Member (România): Teodora Alexa-Stratulat.
  • COST Action CA18103 European Cooperation in Science & Technology – Innovation with Glycans: new frontiers from synthesis to new biological targets. 13.11.2018- 07/04/2023. Management Committee Member (România): Gianina Dodi, Cristina Mariana Uritu.
  • 1HARD/ 4.1/ 93: Cross-Border Integrated Network for Advanced Health Services in Obesity, Diabetes and Metabolic Disorders, project duration: 27.04.2021- 24.04.2023, initial contract amount: 1,439,631 Euro. Project Manager: Monica Hancianu.
  • PN-III-P4-ID-PCE-2020-1247 (contract number PCE 184/2021); Project title: “New challenges in pain therapy: the use of synthetic cannabinoids in chemotherapy-induced chronic neuropathy”; Program type: PN III / PCE; Project duration: 04.01.2021-31.12.2023. Project Manager: Bogdan Ionel Tamba; Initial amount for contracting: 1,198,032 lei.
  • PN-III-P4-ID-PCE-2020-2687; Project title: “Development of new bioactive and biomimetic polymeric nanostructures with applications in wound treatment”; Program type: PN III / PCE; Project duration: 04.05.2021-03.05.2024. Project Manager: Lenuța Profire; Initial amount for contracting: 1,198,032 lei.
  • PN-III-P4-ID-PCE-2020-2393 (Contract No. PCE 204/2021); Project title: “Long-term assessment of cardiovascular risk in patients with CKD following SARS-VOC-2 disease”; Program type: PN III / PCE; Project duration: 04.01.2021-31.12.2023. Project Manager: Adrian Covic; Initial amount for contracting: 1,198,032 lei.
  • PN-III-P1-1.1-PD-2019-0937 (No. PD 225/2021); Project title: “Biodegradable and bioactive 3D composite scaffolds for bone regeneration in osteoporosis (SCAREGOST) / Three-dimensional, biodegradable and bioactive composite supports for bone regeneration in osteoporosis”; Program type: PN III / PD; Project duration: 01.04.2021-31.03.2023. Project Manager: Florina Daniela Cojocaru; Initial amount for contracting: 246,950 lei.
  • INTERNAL GRANT – In vivo evaluation of SPION core-shell theranostic nanoparticles, doped with transition metals for boosting MRI signal. (Contract No. 4716/2021) Period: 01.03.2021-28.02.2023. Budget 47,000 lei. Project Manager: Cristina Mariana Uritu.
  •  INTERNAL GRANT – Preclinical evaluation of canagliflozin as a dual acetylcholinesterase and sodium glucose cotransporter 2 inhibitor in a mice model of scopolamine-induced Alzheimer’s disease-like condition (Contract No. 4715/2021) Period: 01.03.2021-28.02.2023. Budget 23,500 lei. Project Manager: Gabriela Dumitrita Stanciu.
  • ERANET-EURONANOMED-INTREPIDUS-2 (Contract No. 194/2020). Project title: “Nanoporous-Membranes for Intrathecal (Pseudo) Delivery of Drugs (INTREPIDUS)”; Program type: EURONANOMED; Project duration: 16.11.2020-15.11.2023. “Grigore T. Popa” University of Medicine and Pharmacy Iasi – Project partner; Foundation for Biosanitary Research and Innovation of the Principality of Asturias FINBA, Oviedo – Coordinating Institute; Project Manager: Bogdan Ionel Tamba; Initial amount for contracting: 438,800 lei.
  • PN-III-P1-1.1-TE-2019-1671 (Contract No. TE 96/2020); Project title: “Co-encapsulated magnetic nanostructures for teranostic applications in breast cancer: in vivo and in vitro studies”; Program type: PN III / TE; Project duration: 15.09.2020-13.09.2022. Project Manager: Vera Balan; Initial amount for contracting: 431,900 lei.
  • INTERNAL GRANT – New metal complexes of diclofenac derivatives with biological potential. (Contract No. 10308/2020) Period: 01.07.2020-30.06.2022. Budget 23,500 lei. Project Manager: Maria Apotrosoaii.
  • INTERNAL GRANT – The biological evaluation of new multitarget-NSAID derivatives as potential therapeutic agents in inflammatory disease. (Contract No. 6985/2020) Period: 01.04.2020-31.03.2022. Budget 23,470 lei. Project Manager: Alexandru Sava.
  • PN-III-P2-2.1-PED-2019-3970 (Contract No. 357PED / 2020); Mitigation of risk factors for public health, represented by bio-chemical contaminants in food and pharma packaging from recycled sources by a new methodology based on spectral analysis in THz domain; Period 23.10.2020-22.04.2022; Program type PN III / PED; Budget 600,000/400,000 lei; Project Manager: Walther Bild.
  • PN-III-P2-2.1-PED-2019-5446 (Contract No. 429PED / 2020); Smart Health system based on artificial intelligence as a predictor for chronic kidney disease development; Period 23.10.2020-22.10.2022; Program type PN III / PED; Budget 600,000/300,000 lei; Project Manager: Ciprian Rezus.
  • Substitute member of the national network of researchers for the COST Action CA18216 – Network for Research in Vascular Aging; Period 05.11.2019 – 04.11.2023; Project Manager: Adrian Covic;
  • COST Action CA18122: “European Cholangiocarcinoma Network”; Project duration: 18.03.2019 –17.03.2023. Management Committee Member (România): Vasile Liviu Drug;
  • COST Action CA17104 Project title: “New diagnosis and therapeutic tools against multidrug resistant tumors” Project type: COST European Cooperation in Science & Technology – Action CA17104. Development period: 01.10.2018- 01.10.2022. Management Committee Member (România): Teodora Alexa-Stratulat, Cosmin Teodor Mihai.
  • COST Action CA18103 European Cooperation in Science & Technology – Innovation with Glycans: new frontiers from synthesis to new biological targets. 13.11.2018- 07/04/2023, Management Committee Member (România): Gianina Dodi, Cristina Mariana Uritu..

Completed projects

  • PN-III-P2-2.1-SOL-2020-0061 (Contract No. 15Sol / 2020); Project title: 6. Innovative approaches in the treatment and control of patients infected with SARS-CoV-2 virus (CoV-Control); Program type: PN III / Solutions; Project duration: 25.05.2020-05.12.2020. Project Manager: Bogdan Ionel Tamba; Initial contract amount: 309,5000 / 435,000lei.
  • Grant Young Researcher funded by “Grigore T. Popa” University of Medicine and Pharmacy, no. 4718 / 25.02.2021, “Toxicity of glyphosate and glyphosate-based pesticides to human health and environment”. Project Manager: Ioana Cezara Caba.
  • World Bank Research Valorization Program Project. “Polymeric based lidocaine nano-formulation for pain therapy”. Program type: World Bank Research Valorization Program. Project duration: 01.02.- 31.12.2019. Project Manager: Gianina Dodi.
  • Ethical and veterinary assistance: Terranostic antitumor platforms based on carbon dots and polymeric matrices, in accordance with the provisions of the contract for the provision of scientific research services Nr. 10120 / 30.05.2019 (UMF Iaçi) – 12109 / 30.05.2019 (IRO Iaçi): Project Manager: Crina Tiron (Budget: 25,650 lei).
  • INTERNAL GRANT – Development and in vitro evaluation of magnetic nanosystems as multifunctional entities for breast cancer therapy. (Contract No. 27499/2018) Period: 01.01.2019-31.12.2020. Budget 22,900 lei. Project Manager: Vera Balan
  • Project submitted within the Joint Operational Program Romania-Republic of Moldova ENI 2014-2020. Cross-border cooperation. Cross-border integrated network for advanced health services in Obesity, Diabetes and Metabolic Disorders (OBDIA-NET). Project value (part of the “Grigore T. Popa” University of Medicine and Pharmacy): 1,115,245 Euro. Project Manager: Daniel Timofte.
  • INTERNAL GRANT – Development of mass spectrometric and enzyme methods for the investigation of the molecular interaction between neurotoxic amyloid-beta peptide and six selected organic molecules. (Contract No. 27498/2018) Period: 01.01.2019-31.12.2020. Budget 46,550 lei. Project Manager: Raluca Stefanescu.
  •  INTERNAL GRANT – New dressing materials based on Chitosan / PEO electrospun nanofibers for wound healing management. (Contract No. 27496/2018) Period: 01.01.2019-30.06.2020. Budget 23,000 lei. Project Manager: Andreea Teodora Iacob.
  • INTERNAL GRANT Evaluation of cold atmospheric plasma as an associative agent for the improvement of breast cancer chemotherapy effectiveness. (Contract No. 27504/2018) Period: 01.01.2019-31.12.2020. Budget 23,275 lei. Project Manager: Cosmin-Teodor Mihai.
  • PN-III-P1-1.1-PD-2016-1642 (Contract No. 110 ⁄ 2018). Project title: Development of a multifunctional agent such as radiolabeled hybrid magnetic nanoparticles for dual medical imaging (SPECT and MRI); Program type: PNCDI III (2015-2020) – Program 1 – Development of the national research-development system, Subprogram 1.1 – Human resources – Postdoctoral Research Projects; Budget: 250,000 lei; Project duration: 02.05.2018-30.04.2020. Project Manager: Gianina Dodi.
  • Project no. 324 / 05.02.2018 (financing contract). Project title: Setting exposure limits based on health for use in identifying the risk for the manufacture of different medicines, ointments, creams, gels on the same manufacturing flow. Program type: Private financing company Hyperion SA, Iaçi; Budget: 45,000 Lei; Project duration: 05.02.- 20.08.2018. Project Manager: Bogdan Ionel Tamba.
  •  SupraChem Lab – Laboratory of Supramolecular Chemistry for adaptive Delivery systems – ERA Chair initiative, H2020- WIDESPREAD-2014-2015, Project no.667387, ICMPP Iaçi, 2015-2019. Project Manager: Mariana Pinteală.
  • Intelligent therapies for non-communicable diseases based on the controlled release of pharmacological compounds from cells encapsulated after genetic manipulation or vectorized bionanoparticles (INTERA), PN-III-P1-1.2-PCCDI-2017-0697, Beneficiary: Institute of Biology and Cell Pathology „Nicolae Simionescu” Bucharest, 2018-2021. Project Manager: Maya Simionescu
  • PN-III-P1-1.2-PCCDI-2017-0797 (Contract No. 66PCCDI / 2018). Project title: “Pathogenic mechanisms and personalized treatment in pancreatic cancer using multi-homic technologies – PANCNGS”; Program type: PNCDI III (2015-2020) – Program 1 – Development of the national research and development system, Subprogram 1.2 – Complex projects carried out in RDI consortia (PCCDI); Project duration: 04.05.2018 – 31.12.2020. “Grigore T. Popa” University of Medicine and Pharmacy Iasi – Project partner; Fundeni Clinical Institute – Coordinating institution.
  • Establishing exposure limits based on health for use in identifying the risk for the manufacture of different drugs, ointments, creams, gels on the same manufacturing flow; Project type: private financing Hyperion SA Iași; Period: 15.02.2018 – 20.08.2018; Budget: 54,000 lei; Project Manager: Bogdan Ionel Tamba.
  • INTERNAL GRANT – Development of new pioglitazone-curcumin loaded chitosan nanoparticles with potential application in type 2 diabetes mellitus therapy (Contract No. 23401/2018); Period: 01.11.2018-30.04.2021; Project Manager: Sandra Madalina Constantin / Florentina Geanina Lupascu.
  • P-2017-A-02 (CONTRACT NO: 133/2018) Multidisciplinary approach for improving sexual health in female cancer survivors; Period 26.01.2018-25.03.2021; Type of program: Quality assurance in higher education through the training of specialists in the field of Complex Oral Rehabilitation; Budget 8,750 EURO; Project Manager: Lucian Miron.
  • NANOTHERAPLASY: PED no. 245PE / 2017. Advanced diagnosis methods for early gastric cancer through nanoparticle-enhanced THz-based imaging studies. Budget: 475,000 lei. Project Manager: Vasile Drug.
  • GREAT IDEAS UMF Team “Grigore T. Popa” Iași – 18F FDG PET / MRI prognostic markers in Cardiorenal Syndrome (CRS). Budget: 46,500 lei. 01.01.2018-31.12.2019. Project Manager: Mihai Guțu.
  • PN-III-P3-3.1-PM-RO-FR-2016-0040; (Contract No. 93 / BM / 2017). Project title: “Innovative strategy for Alzheimer’s disease: targeting neuroinflammation and DYRK / CLK kinases (New strategies in Alzheimer’s disease: optimization and preclinical validation of innovative agents targeting both protein aggregates and neuroinflammation)”; Program type: Romania-France bilateral cooperation; Project duration: 03.04.2017-31.12.2018. “Grigore T. Popa” University of Medicine and Pharmacy Iasi – Project partner; Contracting budget: 39,055 lei. Project Manager: Lenuța Profen.
  • Project title: Defining competencies in pain management (Contract No. 12318/2017); Program type: International Association for the Study of Pain (IASP); Project duration: 01.07.2017-01.07.2018. Contracting budget $ 9,800; Project Manager: Ostin Costel Mungiu.
  • PN-III-P4-ID-PCE-2016-0126 Project title: Systemic and renal hemodynamic mechanisms in obesity-related kidney injury (Contract No. 44/2017); Program type: PN III / PCE; Project duration: 18.09.2017-31.12.2019. Contracting budget 832,500 lei; Project Manager: Radu Iliescu.
  • PN-III-P2-2.1-PED-2016-1598 Project title: Nanoparticle-enabled Terahertz molecular imaging as advanced early-stage diagnosis of gastric neoplasia (Contract No. 245PED / 2017); Program type: PN III / PED; Project duration: 12.09.2017-31.12.2018. Contracting budget 475,000 / 280,000 lei; Project Manager: Vasile Liviu Drug.
  • PN-III-P2-2.1-PED-2016-1807 Project title: New formulations for topical use in management of chronic wounds (Contract No. PED 151/2017); Program type: PN III / PED; Project duration: 05.04.2017-04.10.2018. Contracting budget 600,000/500,000 lei; Project Manager: Lenuta Profire.
  • PN-III-P1-1.1-PD-2016-1642. Development of a new multifunctional radiolabeled hybrid magnetic nanoparticles like agent for dual medical Imagistics (SPECT and MRI). Project Manager: Gianina Dodi.

National Patents

  • RO134224-A2, Preparing particles of magnetite functionalized with carboxymethyl cellulose used as contrast agent for MRI imaging, by co-precipitating magnetite powder, separating solid product, dispersing and stabilizing, and ultrasonically processing, Samoilă P M; Ciobanu R C; Mihai C T